在生物体内顺乌头酸是柠檬酸在乌头酸酶（定位在线粒体内）作用下异构化生成异柠檬酸的中间产物，这一转变过程受氟乙酸抑制。氟乙酸（常用作灭鼠药）在体内转变为氟乙酰CoA，与草酰乙酸缩合为氟柠檬酸，后者抑制乌头酸酶，阻断柠檬酸转变为异柠檬酸，中止柠檬酸循环，造成致命的后果。
以乙腈为分散剂，采用沉淀聚合法合成了反乌头酸分子印迹聚合物微球。
Microspheric trans aconitic acid imprinted polymers were synthesized via a precipitation polymerization with acetonitrile as dispersion solvent.
通过摇床实验，研究新型阻垢剂乌头酸丙烯酸共聚物(AA AA)的生物降解性。
The biodegradability of the copolymer of aconitic acid-acrylic acid (AA-AA), that is a new kind of scale inhibitor, was studied with shaking-bottle incubating test.
结论：纽蛋白和线粒体顺乌头酸酶参与细胞损伤，可能成为神经防护药物作用的靶点。
Conclusion Vinculin and mitochondrial aconitase may be involved in the cytotoxicity, which may be the target of neuroprotective drugs.
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