正常细胞具有一定的生命周期,只能进行有限次的细胞分裂,癌细胞又称作不死细胞(Immortal cell),如果提供适当的生存条件,癌细胞可以进行无限次的细胞分裂,与此对等的是细胞再生能力,涡虫、蝾螈、蜥蜴可以从截肢处再重新长...
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但一种被称为端粒酶的酶类则可以逆转这个过程;癌细胞之所以不死,其中便有端粒酶的部分功劳。
But there's an enzyme called telomerase that reverses this process; it's one of the reasons cancer cells live so long.
第二是细胞该死的时候不死——有些类型的细胞应该自绝,有时却会失去回应死亡指令的能力。
Another is cells not dying when they ought to - certain types of cells are supposed to turn over and sometimes they lose the ability to respond to signals that tell them to die.
利用基因转染方法使细胞获得不死性,快速建立小鼠胸腺基质细胞(MTSC)系。
For rapid establishment of mouse thymic stromal cell(MTSC) lines, gene transfection was used to immortalize fresh viable cells.
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