ResultsOridonin can strengthen the Nrf2 expression in the liver cells, promote its downstream gene duplication, reduce the active oxygen, and protect livers cells from the damage by ethyl alcohol.
结果冬凌草甲素能增强肝细胞内Nrf2的表达,促进其下游基因的转录,降低细胞内活性氧,减轻酒精对肝细胞的损伤。
参考来源 - 冬凌草甲素通过激活Nrf2通路保护肝细胞的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
最近的研究表明，AP-2能通过与其他蛋白的相互作用来调控AP-2下游基因的转录活性。
Recent studies have shown that interaction partners can modulate the transcriptional activity of AP-2 over the downstream targets.
同时研究了其在各种特定的条件下启动下游基因的表达及其表达量随温度的变化而改变的趋势。
We investigated the expression of GUS which was promoted by this promoter on different situation and the expression trend of GUS quantity go with the change of the temperature.
表皮生长因子受体(EGFR)通路下游基因的激活突变可以引起结直肠癌患者抗egfr耐药。
Activating mutations in downstream genes of the epidermal growth factor receptor (EGFR) pathway may cause anti-EGFR resistance in patients with colorectal cancers.
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