然而，这种疗法在一级预防方面的好处有限。研究表明，服用阿司匹林必须权衡利弊，防止出血的危险。

However, evidence in primary prevention is limited, with studies suggesting that any benefit of aspirin must be weighed against the risk of bleeding.

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在研究过程中两组患者的一级预防均显著性增加。

During the course of study there was a significant and equivalent increase in primary medical prevention in both groups.

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如何及时发现动脉粥样硬化血栓形成高危患者，氯吡格雷在这些患者二级和一级预防中究竟有哪些作用都是值得研究的问题。

How to identify the high-risk patients with atherothrombosis in time, and what roles on earth clopidogrel plays in patients primary and secondary prevention are all the problems to be investigated.

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