这是我犯的一个很大错误。

This is a big mistake I made.

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因为自己的虚荣心，犯下了一个很大错误。

I made a huge mistake to gratify my vanity.

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林·格雷森·波霍尔，一个人力资源管理专家，回忆她曾经的一个犯过一个很大错误的雇员。

Lin Grensing-Pophal, an HR management expert, recalls one of her past employees who made a big blunder.

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A huge one is, are you actually running the code you're looking at in your editor.

一个很大的错误就是你运行的程序,是否是你在编辑器中看到的程序。

麻省理工公开课 - 计算机科学及编程导论课程节选

His popularity at the end of his term, despite what everyone would agree, whether you like Bill Clinton or not, was a big mistake with Monica Lewinsky his popularity didn't suffer very much.

任期结束时，人气很高，尽管大家都心知肚明，不管你喜不喜欢比尔·克林顿，和莱温斯基乱搞男女关系就是一个错误,但是他的人气并未因此受到很大影响。

耶鲁公开课 - 心理学导论课程节选