You've irreversibly changed that substance because you've changed the structure of all the proteins inside.

蛋白质的结构发生不可逆的变化,因为蛋白质内部的全部结构都改变了

耶鲁公开课 - 生物医学工程探索课程节选

If that protein is an enzyme then you've and you've switched it from an 'off' position where it's not catalyzing a reaction to an 'on' position where it is, you've changed the biochemical state of the cell, you've changed the chemical reactions that can occur within the cell, and you've changed its behavior.

如果这种蛋白是一种酶的话,你就能够将酶从无催化作用的静息态,激活至能催化反应的激活态,你改变了细胞的生化状态,也改变了细胞内发生的化学反应,改变了细胞的行为

耶鲁公开课 - 生物医学工程探索课程节选

"You've got to remember who you've changed, who you've fed, " she says.

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Unless you've changed the default settings on your email, you are treated to a pop-up message, the sound of a bell, or a counter that signals your growing number of unread messages.

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" And men - the explorers, have the opposite complaint, "You've changed.

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