Are you tired? Worn out?

你是不是累了，筋疲力尽了？

youdao

Are you tired of eating the same food every day?

你厌倦了每天吃同样的食物吗？

youdao

Playing sports makes you tired but completely relaxed.

做运动让你很累，但却能完全放松。

youdao

If you are tired after hitting all those nails on the head, then it is time to hit the hay.

VOA: special.2009.09.20

When you're really tired sleep is what you want to do like when you're really hungry you want to eat.

你累了，就会想睡觉,正如你饿了想吃东西一样。

耶鲁公开课 - 心理学导论课程节选

You'd be less likely to say "You look tired." or "You look bored." or "You look strange."

但你可能并不会说，“你看起来累极了。”，或者“你看起来很无聊。”，或“你看起来很奇怪。”

You look 课堂 - SpeakingMax英语口语达人

Caffeine works by suppressing the neurotransmitters in your brain that would normally release nerve impulses that make you tired.

CNN: Caffeinated moms drink up to keep up

Are you tired of leading-edge boomers controlling American political life?

FORBES: Baby Boomer Brand Beaten Up

Aren't you tired of hearing about Peak Oil?

FORBES: Magazine Article