She never had the least idea what to do about it.

这事怎么办，她一点主意都没有。

《牛津词典》

As sleep-deprived people ourselves, we started thinking of what to do about it.

作为睡眠不足的人，我们开始思考该做些什么。

youdao

The question? What to do about it?

问题来了， 该怎么办？

youdao

Sometimes he seems to be saying, "I'm not happy about anything, but what are you going to do about it?"

VOA: special.2010.01.17

How do we have a conversation about what does it mean to be a well-rounded student at an American university today?

我们如何建立这样一个对话,就是在当今的美国大学中,如何才能成为一个全方位发展的学生？

普林斯顿公开课 - 人性课程节选

I'm not going to do it for you, but what would I think about doing when I change the code?

要改变代码应该做什么呢？,我不会帮你们做这些,但是我在改编代码的时候会想什么呢？

麻省理工公开课 - 计算机科学及编程导论课程节选

It's a sly idea and no one seemed to know what to do about it.

FORBES: Magazine Article

The economy is a worry, but no one really knows what to do about it.

ECONOMIST: Prison reform

Both men understand the danger, but have no idea what to do about it.

ECONOMIST: Tony Blair and Gordon Brown can't go on like this