He would start writing to his family and would screw the letter up in frustration.

他一次次开始给家里写信，又一次次懊恼地把信揉成团。

《柯林斯英汉双解大词典》

They can screw us up and set us back.

它们会搞砸我们的事，阻碍我们的脚步。

youdao

This is an easy one to screw up.

这是一个很容易弄糟的错误。

youdao

Thank you. Nice catch too by the way. All right, so now that you can see that I can screw up programming, which I just did.

但是我们在半路中发现并修复了，谢谢你，那么我们做了什么呢？,我们现在学习了收集东西的一种方式。

麻省理工公开课 - 计算机科学及编程导论课程节选

I'm going to look desperately at my T.A.'s to make sure I didn't screw that up.

我得问问助教们,检查一下我是否算错了

耶鲁公开课 - 博弈论课程节选

If you screw it up we don't count it as much as if you do well.

你要是期中考砸了就给你在总评里降低期中比例

耶鲁公开课 - 1871年后的法国课程节选

Here, nobody gets fired regardless of how they screw up or who they screw.

CNN: Office talk: Have your say

So when I screwed up, the consequences weren't as high as when kids on the South Side screw up. (Applause.) So I had more of a safety net.

WHITEHOUSE: Hyde Park Career Academy Chicago, Illinois

"You screw up the fundamentals, you're not supposed to win, " Blue Jays manager John Gibbons said.

WSJ: Loup's throwing error helps Yankees beat Blue Jays