Protein tyrosine nitration is an important posttranslational modification involving a variety of diseases.

蛋白质酪氨酸硝基化是一种重要的蛋白质翻译后修饰，与多种病症相关。

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AIM to study the effect of fructose 1, 6 diphosphate (FDP) on adriamycin (ADM) induced myocardial tyrosine nitration in rats.

目的研究1,6二磷酸果糖(FDP)对阿霉素(adm)导致大鼠心肌酪氨酸硝基化的影响。

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CONCLUSION FDP can inhibit myocardial tyrosine nitration induced by ADM, and thereby reduce injury of cardiotoxicity induced by ADM.

结论FDP抑制adm导致心肌酪氨酸硝基化而减轻adm对心肌的毒性损伤。

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One mechanism of oxidative damage is the nitration of tyrosine residues in proteins, mediated by peroxynitrite breakdown.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup

Although carbonyl formation is a major oxidative modification induced by peroxynitrite, nitration of tyrosine residues is an indicator of peroxynitrite involvement.

FORBES: The Lessons Of Failure: What We Can Learn From Bapineuzumab's Blowup