肾小管间质纤维化(Tubulointerstitial fibrosis)是各种炎症和非炎症肾脏疾病进展的最终结局。肾小管间质细胞表型转化、致纤维化细胞因子过度表达、细胞外基质(extracellular mat...
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众所周知，肾小管间质病变程度直接影响疾病的预后，尤其是肾间质纤维化(tubulointerstitial fibrosis，TIF)是各种人类和实验性肾脏疾病进展至肾功能衰竭的共同途径，在各类慢性肾脏疾病中，肾小管间质病变的程度是判...
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众所周知，肾小管间质病变程度直接影响疾病的预后，尤其是肾间质纤维化(tubulointerstitial fibrosis，TIF)是各种人类和实验性肾脏疾病进展至肾功能衰竭的共同途径，在各类慢性肾脏疾病中，肾小管间质病变的程度是判...
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...缓阿霉素肾病大鼠肾损伤 褐藻多糖硫酸酯对阿霉素肾病肾硬化大鼠 【中文摘要】目的肾间质纤维化(Tubulointerstitial fibrosis,TIF)是慢性肾脏疾病进展至终末期肾功能衰竭的必然病理变化。
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Renal tubulointerstitial fibrosis 肾间质纤维化 ; 肾小管间质纤维化 ; 肾小管 ; 间质纤维化
Tubulointerstitial fibrosis TIF 间质纤维化
tif tubulointerstitial fibrosis 肾小管间质纤维化
Renal tubulointerstitial inflammation and fibrosis 肾间质炎症和纤维化
In rats that received high-salt diet,severe tubulointerstitial fibrosis were also observed.
高盐饲料喂养导致了DS大鼠严重的肾小球硬化以及肾间质纤维化。
参考来源 - 氨氯地平和依普利酮联合应用在缓解盐敏感高血压所致肾脏损害中作用机制的研究Tubular epithelial myofibroblast transdifferentiation(EMT) is an important pathomechanism of renal tubulointerstitial fibrosis.
肾小管上皮细胞转分化(tubular epithelial to menchymal transdifferentiation,EMT)是肾小管间质纤维化的重要病理机制之一。
参考来源 - 逆转肾小管上皮细胞转分化的Smad信号转导机制Objective: ① To establish a ideal animal model of partial unilateral ureter obstruction (PUUO). ② To investigate the degree of hydronephrosis,the change of renal function, and the development of tubulointerstitial fibrosis caused by PUUO.
目的:① 探索建立一种理想的输尿管部分梗阻的动物模型,② 观察部分梗阻引起的肾积水、肾功能损害及肾纤维化的程度,③ 在不同时间段解除梗阻后检测肾功能及肾纤维化恢复的程度,从而为临床治疗提供依据。
参考来源 - 输尿管部分梗阻所致肾积水、肾纤维化的实验研究Therefore it is significant to explore the trigger factors and the relevant mechanisms of tubulointerstitial fibrosis and seek the early reversible factor or treatment.
因此探讨促发。 肾小管问质纤维化的因素和相关机制,寻求其早期可逆因子或防治措施对肾脏疾病转归有重要意义。
参考来源 - 组织型转谷氨酰胺酶与转化生长因子β1在幼鼠肾间质损伤中的表达及意义·2,447,543篇论文数据，部分数据来源于NoteExpress
To evaluate the effect of estrogen on tubular epithelial cell phenotype transdifferentiation of tubulointerstitial fibrosis in unilateral ureteral obstruction(UUO)rats.
目的探讨雌激素在单侧输尿管梗阻（UUO）大鼠肾间质纤维化模型中对肾小管上皮细胞表型转化的影响。
Therefore it is significant to explore the trigger factors and the relevant mechanisms of tubulointerstitial fibrosis and seek the early reversible factor or treatment.
肾小管问质纤维化的因素和相关机制，寻求其早期可逆因子或防治措施对肾脏疾病转归有重要意义。
The imbalance of interstitial cell proliferation and apoptosis and the metabolic disorder of intercellular substance, are two essential factors for renal tubulointerstitial fibrosis.
间质细胞增殖和凋亡失衡及细胞间质代谢失调也是造成肾小管间质纤维化的两个不可缺少的原因。
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