The biggest problem is that readers online bring in nowhere near the revenues that print readers do.

最大的问题是，网上读者所带来的收益远不及印刷版读者带来的收益多。

youdao

Analysts say the biggest problem is high unemployment, which weakens demand and makes banks reluctant to lend.

分析者说，最大的问题是高失业率，这会导致借贷需求减少以及银行不愿意放贷。

youdao

The biggest problem is that couples assume each other knows what's going on with their finances, but actually they don't.

最大的问题是，夫妻双方都认为对方知道他们的财务状况，但事实并非如此。

youdao

She says the biggest problem was feeling very alone as a woman in science.

VOA: special.2009.05.13

What do you think is the biggest problem about living in LA?

你觉得住在洛杉矶最大的问题是什么？

大众交通枢纽 - SpeakingMax英语口语达人

And Widow Maker,in the end, caused the biggest problem for Pecos Bill.

VOA: special.2009.11.28

The biggest problem Google is likely going to encounter is a demoralized organizational culture.

FORBES: Is Google Crazy? Or Crazy Like a Fox?

Perhaps the biggest problem facing IT today is that its accounting practices are substantially immature.

FORBES: The Coming Crisis of IT Management

In the end, that is the biggest problem for proponents of new approaches to nuclear energy.

ECONOMIST: The prospects