While the opening of "Men In Black 3" didn't disappoint at the box office and far exceeded the haul of "Battleship" the other big-budget film to challenge "The Avengers" its showing failed to maintain the exceptional momentum sparked by the presummer opening of the superhero action film.
Given was left reminding Wall Street that the FDA process is a "black box" and that he couldn't give any details of the company's negotiations with regulators, which are confidential.
In a perspective published online Monday night in The New England Journal of Medicine, Nissen lays out his case that drugs such as Ritalin, Concerta and Adderall may cause potential risks to the heart that many patients don't appreciate--and that these risks should be spelled out in a clear, black-box warning for consumers.