It is showed that the degeneration effect of MMP-7 and MMP-9 on supporting structure in anal cushion is one important mechanism of pathogenesis and development of hemorrhoids, and MMP-7 and MMP-9 may be have a synergism effect on the process.
MMP-7、MMP-9在痔组织中的表达明显高于正常肛垫,而且两者呈正相关关系,提示其对肛垫周围固定支持组织的降解作用可能是痔形成及发展的一种重要机制,而在这一过程中,二者间可能具有协同作用。
参考来源 - MMP·2,447,543篇论文数据，部分数据来源于NoteExpress
Models of transplanted tumor in mice and human cancer xenograft in nude mice were used to evaluate the antitumor effect and synergism of total alkaloid of Peganum harmala l, (TAH).
用小鼠移植性肿瘤和裸鼠异体移植人肿瘤模型研究骆驼蓬总碱(TAH)抗肿瘤作用及其协同抗瘤作用。
The results showed that the combined effect of NP and BPA was greater than the sum of their individual effects. The interaction of NP and BPA was synergism action.
将联合暴露结果与单一暴露结果进行对比，结果表明，NP和BPA联合作用时，对斑马鱼的雌激素效应远大于单一毒物雌激素效应之和，二者相互作用时表现出协同效应。
The major synergism between the ESP unit and the baghouse unit is a technical difficulty for its effect on the efficiency of the dedust system and the operating life of the filter-bag.
其中静电除尘单元与布袋除尘单元之间的结合形式是一个技术难点，因为其将影响整个除尘系统的效率和布袋的使用寿命。
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