That subtle change adds 5% more responses.
小小的改变增加了5%的回应。
He perceived a subtle change in her manner.
我察觉到他的态度有一个微妙的改变。
Her whole attitude had had a subtle change.
她的整个态度发生了微妙的变化。
Sometimes that subtle change can lead to a big change in the function of the protein.
有时候,蛋白质在结构上的小小改变,会导致其功能发生巨大变化
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