Advanced gout. Untreated gout may cause deposit of urate crystals to form under the skin in nodules called tophi (TOE-fi).

未经治疗的痛风会使皮肤下沉积尿酸结石从而形成结节，成为结节瘤。

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Patients mayshow extensive, bilaterally symmetric, nonanesthetic skin lesions with macules, nodules, plaques, or papules.

患者皮肤会出现广泛的，双侧对称性的斑点、结节或斑块。 但并没有无痹感（仍有感觉）。

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The result is a large number of nodules and cysts that deeply penetrate the surface of the skin.

其结果是大量的结节和囊肿深受穿透表面的皮肤。

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These fats can fill macrophages to form small to large nodules under the skin called xanthomas.

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