Several DNA damage-induced signaling cascades,including ATR/Chk1, jun N-terminal kinase and p38 kinase pathways areactivated following UV radiation, leading to the activation of NER andrecovery mechanisms via transcription factors such as p53, NF-kB andAP-1.
紫外线辐射导致的DNA损伤通过信号级联反应活化ATR／Chk1、jun、p38 MAPK等信号通路，从而导致核苷酸切除修复(NER)及p53，NF-κB和AP-1等转录因子介导的修复过程的启动。
参考来源 - 绿茶提取物光保护作用系列研究·2,447,543篇论文数据，部分数据来源于NoteExpress
The effect of insulin is highly associated with IRS1 signaling cascades.
胰岛素的这种作用与IRS1信号转导通路密切相关。
Autophagy is regulated by an intricate network of signaling cascades that have not yet been entirely disentangled.
通过一种尚未完全了解的级联信号的复杂网络(系统)，可以调节自噬。
In vertebrates, IRS-2 functions as a scaffolding protein to coordinate separate branches of the Insulin/IGF-signaling cascades (2).
在脊椎动物中，IRS-2以脚手架蛋白发挥作用，协调胰岛素/IGF信号级联通路中的不同分支（2）。
应用推荐