Conclusion: This design method can provide a safe and effective dosage for clinical administration and can evaluate a dosage regimen.

结论：设计方法简单，使用方便，既能为临床用药提供安全有效的剂量，又能对某一用药方案作出评价。

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Conclusion TGP combined with low dosage methotrexate is effective and safe scheme on elderly onset rheumatoid arthritis.

结论白芍总苷联合较小剂量甲氨蝶呤治疗老年起病类风湿关节炎为有效、安全方案。

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Conclusion: Subclincal dosage of antidepressant is an effective and safe drug for treatment of refractory IBS.

结论：小剂量抗抑郁药是治疗难治性结肠易激综合征的安全和有效的药物。

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