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Barkley added all four conversions and the one sour note for Bath was scrum-half Michael Claassens's sin-binning for cynically killing the ball at a ruck right on the hosts' tryline.
BBC: Bath 66-21 Saracens
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The home side were briefly reduced to 14 men themselves when, with Northampton camped on Sale's line, scrum-half Peel incurred the wrath of referee Tim Wigglesworth and became the first of the night's three sin-binnings for kicking the ball out of Martin Roberts' hands as he attempted to take a quick penalty tap.
BBC: Sale Sharks 29-21 Northampton Saints
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They could not cross the visitors' line but a third Lamb penalty, with Munster's Tuitupou in the sin bin for a spear tackle on Stringer, followed by a short-range drop-goal, gave the hosts a 12-3 lead.
BBC: London Irish 23-17 Munster