The progressive result is an accumulation of fatty deposits called plaque that can rupture or have their caps shear off, causing clots that lead to heart attacks.

Donohue博士说，进一步恶化的结果是称之为血斑的脂肪沉积开始积累、破裂、剥落，最后形成导致心脏病发作的血栓。

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Over time, the buildup of plaque deposits can rupture and cause total blockage of the blood flow to the heart.

久而久之，血小板沉积物逐渐积累，会导致流往心脏的血液完全阻塞。

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The act of exercising, however, may increase the risk that the plaques will rupture, precipitating a heart attack.

而且，运动时的动作可能会增加斑块破裂的风险，引发心肌梗死。

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Just last month, researchers led by Armin Arbab-Zadeh of Johns Hopkins University School of Medicine in Baltimore published a comprehensive review of the biology of heart attacks in the journal Circulation, which said that vulnerable plaques often rupture without causing a heart attack and that a "perfect storm" of other conditions is required before one occurs.

WSJ: Predicting Who Will Have Heart Attacks

Researchers now believe that up to 85% of heart attacks occur when arterial plaques suddenly rupture, spilling toxic substances and triggering a massive clot.

FORBES: Anatomy Of A Heart Attack