The RUPPnetworkconductedtwomajortrials. In the firsttrialchildrenwith autismaccompanied bytantrums, aggressionand self-injury were treated with the antipsychoticrisperidone (Risperdal).
The drugs are aripiprazole, sold under the brand name Abilify,olanzapine, also known as Zyprexa, quetiapine whose brand name is Seroquel, and risperidone sold under the brand name Risperdal.