OBJECTIVE to study the mutation in DNA gyrase a of Escherichia coli resistante to quinolone antibiotics.
目的研究导致大肠埃希菌dna回旋酶a亚单位的基因变异耐喹诺酮类药物的机制。
Norfloxacin is one of the outstanding representatives of the third generation of quinolone antibiotics, and there are a good deal of methods for synthesizing it.
氟哌酸是第三代喹诺酮类抗菌药物的优秀代表之一，它的合成路线有很多种，而以形成硼螯合物的方法倍受关注。
Do antibiotics sensitivity test on its recombinant strains, but no resistance of Quinolone can be found.
药敏试验结果表明，重组菌株失去对喹诺酮类药物的抗药性。
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