研究发现,耐药性的产生主要与聚合酶基因(Polymerase gene)变异有关。两种或多种药物的联合或序贯应用等方式,或更新的核苷类药物如阿德福韦等的应用,可减少耐药性的产生。
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dna polymerase gene dna聚合酶基因
RNA polymerase gene RNA聚合酶Ⅰ基因
3D polymerase gene D聚合酶基因
pb polymerase gene 聚合酶pb1基因
PB1 polymerase gene 聚合酶PB1基因
pb 1 polymerase gene 聚合酶pb基因
dna polymerase gene pola dna多聚酶i基因
poly adp-ribose polymerase gene 聚腺苷二磷酸核糖聚合酶基因
poly adp-ribose polymerase- gene 聚腺苷二磷酸核糖聚合酶
Small t antigen could activate of the RNA polymerase gene promoter,as well as c-myc and c-fos oncogene transcription,repress cytoplasmic actin transcription and decrease cellular adhesion.
t抗原能反式激活RNA多聚酶基因的启动子,以及c-myc和c-fos癌基因转录,使细胞质肌动蛋白缺失和细胞粘附性下降。
参考来源 - SV40T抗原基因诱导可逆性永生化黑素细胞的生物学特征评价·2,447,543篇论文数据，部分数据来源于NoteExpress
A specific semi-nested RT-PCR based on the RNA-dependent RNA polymerase gene in AF469603 of Chinese bee (Apis sinensis) sacbrood virus was established to detect Chinese bee sacbrood virus.
基于中蜂囊状幼虫病病毒基因组序列AF469603中的RNA依赖的RNA聚合酶基因，建立该病毒的半套式RT-PCR检测方法。
Eligible patients were hepatitis B surface antigen-positive men and women with compensated liver disease who were given lamivudine at least more than 6 months and had HBV polymerase gene mutation.
符合条件的患者乙肝表面抗原阳性的代偿性肝脏疾病的男性和女性谁是至少6个月以上的，给予拉米夫定和HBV聚合酶基因突变。
AIM: To establish the mutant of coding calcium binding fragment of the 13th exon of human thrombospondin-1 (TSP-1) gene with polymerase chain reaction (PCR) site directed mutagenesis technology.
目的：利用聚合酶链反应定点突变技术构建人血小板反应素1基因第13外显子编码钙结合域突变体。
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