Objective: To observe the expression of poly (ADP-ribose) polymerase (PARP) in focal cerebral ischemia with reperfusion injury and explore the role of PARP in apoptosis.

目的观察多聚ADP 核糖聚合酶（PARP）在脑缺血再灌流损伤中的表达，探讨PARP在细胞凋亡中的作用。

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The cleavage of Poly(ADP ribose)polymerase(PARP) is an molecular event of the activation of cysteine protease, and it is also an early molecular marker of apoptosis .

的蛋白酶解为半胱氨酸蛋白酶激活的分子事件，是细胞程序死亡的一个早期分子标志。

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By blocking these errant molecules, D-serine and poly ADP-ribose polymerase (PARP), researchers may be able to stop brain cells from dying while avoiding the toxic side effects that have plagued previous experimental treatments.

FORBES: Repairing The Brain

By blocking these errant molecules, called D-serine and poly ADP-ribose polymerase, known as PARP, researchers may be able to stop brain cells from dying, while avoiding the toxic side effects that have plagued previous experimental treatments.

FORBES: Repairing The Brain

Gleason also cites a new class of drugs known as PARP (poly ADP-ribose polymerase) inhibitors, which appear to be highly effective in treating breast cancer patients with certain mutations, and finally the sale of new products that could earn new markets.

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