AIM: To establish a new method for calculating the pharmacokinetic parameters of bi-compartmental drugs based on the plasma level of the drug during the intravenous infusion phase.
目的：建立一种根据血药浓度的微分特征计算静脉滴注双室模型药物动力学参数的新方法。
Only recently have the peroral or dermal use been evaluated. Drugs encapsulated into SLN showed a reduced peak plasma concentration and prolonged therapeutic drug level following oral administration.
近年来，SLN的口服和经皮给药逐渐受到重视，研究发现，口服经过SLN包裹后的药物能降低其血药浓度峰值，并延长药物作用时间。
Drug products that have similar AUCs but differently shaped plasma-level curves are equivalent in extent but differ in their absorption rate-time profiles.
一些AUC相同而血浆浓度曲线形状不同的药物，具有相同的吸收分量和不同的吸收速率-时间。
应用推荐