根据化学结构,临床常用的钙拮抗剂均可分为苯烷基胺类(Phenylalkylamines),如维拉帕米、加洛帕米(Gallopamil)等;二氢吡啶类(Dihydropyridines, DHPs),如硝苯地平、尼莫地平等;苯硫氮类(Benzothiaze...
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The linear equation shows that the benzene ring and the nitrogen atom should be the active sites of phenylalkylamines and they would interact with the acceptor acting as electron donors.
同时所得线性方程表明:33个苯烷基胺类化合物作为电子给体与受体发生作用,苯环和氮原子是其活性部位。
参考来源 - 苯烷基胺类迷幻剂的定量结构—活性关系(QSAR)研究·2,447,543篇论文数据,部分数据来源于NoteExpress
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