French Open and Wimbledon champion Rafael Nadal will face Jesse Levine after the American qualifier beat Canadian wildcard Peter Polansky 6-2 6-4.

BBC: Djokovic opens defence in style

Fellow American James Blake beat Peter Polansky of Canada 6-7 (1-7) 6-3 6-2 6-4, while Spain's 22nd seed Juan Carlos Ferrero defeated Ricardo Mello of Brazil 6-1 6-4 6-4.

BBC: Roger Federer wins at US Open as Davydenko & Cilic lose

Latvia's Gulbis, seeded 24th, lost in straight sets to Jeremy Chardy , 28th seed Radek Stepanek lost 6-4 6-2 4-6 6-4 to Julien Benneteau and 30th seed Juan Monaco was sent packing by Canada's Peter Polansky in straight sets.

BBC: Rafael Nadal beats Teymuraz Gabashvili at the US Open