Then in early 2005, one of BioMarin's largest shareholders, health care-focused money management fund OrbiMed Advisors, launched a proxy battle in which it requested three new board members.

FORBES

Another example he gives: When Pharmacopeia (nasdaq: PCOP - news - people ), a biotechnology company, tried to buy EOS , a privately held firm, Orbimed Advisors, Pharmacopeia's biggest shareholder, launched a vocal critique that sunk the deal.

FORBES: ICN Shareholders Win. Now What?