To verify the curative effect and safety of lamotrigine (LTG) for the treatment of childhood epilepsy, a open-label, add-on, self-control study was undertaken on 44 children with intractable epilepsy.

为验证拉莫三嗪治疗儿童癫痫的疗效和安全性，对44例儿童顽固性癫痫进行了开放性自身对照研究。

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Although the study was open label, the assessment of outcome events was blinded.

尽管这项研究是标签公开的，结果的评估是盲目的。

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In the safety study, a 52-week open-label trial, Dr. Wortzman and colleagues reported clindamycin-tretinoin gel to be safe and well tolerated in 655 patients (mean age, 20 years).

在52周的开放性安全试验中，Wortzman博士及其同事报告，655名患者(平均年龄20岁)使用克林霉素-维甲酸凝胶显示安全有效且耐受良好。

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Schneider CK, Melmed RD, Barstow LE, Enriquez FJ, Ranger-Moore J, Ostrem JA. Oral Human Immunoglobulin for Children with Autism and Gastrointestinal Dysfunction: A Prospective, Open-Label Study.

FORBES: Anti-Vaccine Activists Apparently Immune To Science

Announcing the failure of the latest trial Tuesday, the two companies said they would halt development of Dimebon for all indications and cease an ongoing open-label extension study in Alzheimer's disease.

WSJ: Medivation, Pfizer Alzheimer's Drug Fails to Meet Study Goals

The study was a multinational, single-arm, open-label, 78 week trial that was recently published in the November 2, 2012 online version of the Lancet.

FORBES: FDA Approves Lomitapide For Homozygous Familial Hypercholesterolemia