【Key words】 Gene therapy； Non-viral vectors； Targeting delivery； Reporter gene； Interleukin-12； Liposome-polycation-DNA complexes；
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Polyaminoacid materials are widely researched as non-viral gene vectors because of the advantages, such as biodegradation, low cytotoxicity and so on.
聚氨基酸材料由于可生物降解性，低毒性等特点而被广泛的作为非病毒性基因载体材料的研究。
The recent topic has been focused on the new non-viral vectors.
因此寻找新的非病毒载体成为目前的研究热点。
Conclusion LPD could be prepared easily with small particle sizes and high transfection activities. LPD may be good non-viral vectors for applications in gene delivery.
结论LPD是一种制备工艺简单、体外稳定性好、转染率高，具有应用潜力的非病毒载体系统。
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