A key step would be to perform a natural history study that would follow people over a number of years and track in more detail how HPV-oral infections lead to cancer.

关键的一步，将执行一个自然历史研究会按照更详细的数量超过年和跟踪的人如何HPV口腔感染导致癌症。

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Ms Frizzles and the gang just want to study dinosaurs at the Museum of Natural History.

弗瑞斯夫人和孩子们现在要去自然历史博物馆里学习恐龙知识啦！

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Most cases are still seen in women older than 40 years, and in this study, they were 15 to 26 years old, so the natural history of VIN2-3 lesions in such a young person is not really known, she said.

大部分的病例常发生在年龄大于40岁的女性，而本研究中女性都在15至26岁，因此在这些年轻人群中VIN2 - 3损伤病史仍不清楚，她说。

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McCarty, an investigator at Nationwide's Center for Gene Therapy, says relying on another researcher's data from a natural-history study would be problematic.

WSJ: Families Push for New Ways to Research Rare Diseases

And even if a natural-history study leads to a clinical trial for a treatment, there is no guarantee the same children will be allowed to participate.

WSJ: Families Push for New Ways to Research Rare Diseases

When he heard about the natural-history study being planned by Nationwide, Mr. Zeighami says he wondered why they had to redo data that Shire might already have.

WSJ: Families Push for New Ways to Research Rare Diseases