Based on the observationmentioned above, we speculate that the circulating SPCs home to the wall of PA under hypoxia, and sequently differentiate into VSMCs under the control of myocardin, whichlead to the muscularization of non-muscular pulmonary arterioles.
鉴于以上研究基础,我们设想:在慢性低氧条件下,循环SPCs归巢至肺无肌细动脉,在myocardin的调控下分化为VSMCs从而参与了低氧性肺无肌细动脉的肌化。
参考来源 - 循环平滑肌祖细胞在低氧性肺无肌细动脉肌化中的作用·2,447,543篇论文数据,部分数据来源于NoteExpress
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