(新页面: {{BBAHeader}} ;模拟表位(Mimotope): A '''mimotope''' is a macromolecule, often a peptide, which mimics the structure of an epitope.
基于26个网页-相关网页
Oligo-peptide containing mimotope with high antigenicity can substitute for large antigen segment to be used in the study of the structure and function of the key antigenic sites on viruses, and provide a valuable clue on prevention, diagnosis and treatment.
利用单克隆抗体(mAb)淘筛噬菌体肽库,可以得到相应的抗原或抗原表位,有助于了解病毒受体关键位点的结构和功能,为病毒受体的鉴定和分离提供有益的线索。
参考来源 - 利用噬菌体肽库筛选汉滩病毒受体结合表位的研究Up to now, many hemagglutinin-neuraminidase (HN) nucleotide sequences of NDV strains were obtained, but there is still few reports about its mimotope.
目前已获得多株NDV血凝素—神经氨酸酶(HN)的基因核苷酸序列,但对其抗原模拟表位的研究还鲜有报道。
参考来源 - 新城疫病毒血凝素—神经氨酸酶模拟表位及其免疫生物学特性研究·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
Objective:To obtain the mimotope of avian infectious bronchitis virus by phage display peptide library.
目的:利用噬菌体展示肽库技术筛选鸡传染性支气管炎病毒的模拟抗原表位。
Methods (1) The coding sequence of MG7 mimotope (GC23) was included in the reverse primer, and by PCR incorporated with HSP70 gene at the 3 terminus.
方法1。根据HSP70全长基因序列设计针对其编码区的引物,在下游引物的宁端加人MG7模拟表位的核昔酸序列。
A competitive ELISA was set up with a mimotope peptide conjugated to BSA carrier, and the new method was compared with conventional ELISA method and HPLC method.
将化学合成的模拟表位肽与载体BSA偶联后,以之建立无毒素的竞争酶联免疫检测方法,并与常规酶联免疫吸附检测方法及高效液相色谱比较。
应用推荐