Mechanical stimulation can induce the rearrangement of the cytoskeleton, and the signals are transduced and transformed by the second messagers, finally resulting in the changes of gene expression.

力学刺激可引起骨架纤维重排并可借助第二信使将力学信号传递并转换，最终调节基因的表达。

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Most e-mailers and text-messagers do not consult etiquette coaches, though, and with the demise of words-on-paper letters, the future of "Dear" appears dire.

CNN: Is 'Dear' dead?