Lymphocytes are a type of white blood cell involved in immune function and are categorized as either B-cells or T-cells. This newly discovered element, CD19-L, is expressed on the surface of T-lymphocytes and allows them to selectively bind to the CD19 receptor on the surface of B-lineage leukemia cells, and most importantly on leukemic stem cells responsible for the survival and expansion of the leukemia cell population. Once the CD19-L binds to leukemia cells, cell death occurs. Although CD19 is abundantly expressed on leukemia cells from B-lineage ALL patients, it is absent on red cells, T-cells, and normal bone marrow stem cells, making it specific, and therefore, a good therapeutic target.
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To the specific question that Mr Carr asks about what the Internet is doing to our brains, the simple answer is that it is making us think and behave differently.
对于卡尔先生所问的具体问题:电脑对我们大脑造成了什么样的影响,简单的答案就是使我们想的和做的与以前不同了。
It doesn't require any specific technology at the endpoints, making it completely agnostic to vendors, platforms, and technologies.
它在端点不需要任何特定的技术,因此完全不需要知道所用的供应商、平台和技术。
Type 4 is even more problematic because it requires the portal page to change and making the portlet show a specific piece of content.
类型 4 的问题更多,因为它需要修改门户页面而且需要 portlet 显示特定内容块。
So, making gene therapy specific is a key problem in making it work.
所以基因治疗中,特异性对能否成功就至关重要了
First of all, it suggests of course that he was giving language to something, making a specific image out of something, that didn't quite have that specific content in his experience as a child.
第一,这的确可以反映出,他是在描述东西,运用某种东西来描述一个形象,在他作为孩子的经历中,那东西没有特殊的意义。
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