Large numbers of permanent employees make it difficult for organizations to respond quickly to downturns in demand by decreasing payroll costs.

大量的固定雇员使得企业很难通过降低工资成本来迅速应对需求下降。

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Thus, fever would make it more difficult for an infecting bacterium to acquire iron and thus to multiply.

因此，发烧会使感染细菌更难获得铁，从而更难繁殖。

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Some immigrant advocates worry that hard financial times make it more difficult for natives to keep jobs.

一些移民拥护者担心，经济困难会令当地人很难保住工作。

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This makes it more and more difficult for them to make friends and more likely that society will reject them.

VOA: special.2010.01.06

and a number of things that are just, sort of, difficult for human beings to process and make intelligent decisions.

还有一系列，人们难以去控制,并且做出正确决定的事情。

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But for all that, thinking about those facts make it rather difficult, while you're thinking about the facts, to continue enjoying kissing the person.

但是尽管如此，想到这些事实让继续享受亲吻，变得困难了，当你想到这些事实时。

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High prices for corn, beef, and other staples right now make it difficult for a one-location restaurant to price competitively and still make a profit.

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Delinquencies cause the credit card companies to cut credit limits for existing customers and make it difficult for new customers to get cards.

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"It's very difficult to go out of the Champions League for anybody, especially when you lose at home, you make it difficult for yourself, " Wenger told Sky Sports.

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