The worst cases result in internal bleeding, circulation problems, and liver enlargement.

最严重的会导致内出血、循环系统问题和肝肿大。

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Symptoms include high fever, joint pains and nausea, but in severe cases, it can lead to internal bleeding, liver enlargement, circulatory shutdown and death.

发病症状有高烧、关节疼痛、恶心呕吐，严重病症可能会发生内出血，肝增大，循环系统衰竭和死亡。

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Liver enlargement is common in advanced cases, and is frequently associated with an accumulation of fluid in the peritoneal cavity and hypertension of the abdominal blood vessels.

肝脏肿大是晚期病例的常见症状，往往与腹腔积水及腹腔血管高压有关。

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In humans, symptoms typically include skeletal deformities, mental retardation and abnormal enlargement of the spleen and liver.

MSN: Cause of rare and fatal dog skeletal disease pinpointed