Lipophilicity parameters 疏水性参数
lipophilicity index 亲脂指标
Increased lipophilicity 增加亲脂性
ligand-lipophilicity efficiency 配体
Lipophilicity is an essential feature for the penetration of a molecule through the blood-brain barrier, so we designed some structurally-related agmatine derivatives with better lipophilicity (substituting guanidine with 2-nitroethene-1,1-diamine or N-cyanoguanidine).
在本论文中，以胍丁胺为先导化合物，将胍基替换成一些亲脂性较好的相关基团（如：N-氰基胍基或2-硝基乙烯-1，1-二胺基），以期改善其血脑屏障通透性和药代动力学性质。
参考来源 - 胍丁胺衍生物的设计合成及生物活性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
Second, the selectivity depends on the Coulomb interaction on the surface, not the lipophilicity.
第二，选择性只与表面的库伦作用力有关。
Drugs with low lipophilicity (ie, low membrane permeability), such as aminoglycosides, are absorbed slowly from solution in the stomach and small intestine;
低亲脂性（即膜通透性低）药物，如氨基糖苷类，经胃和小肠溶液被缓慢吸收。
Objective:To investigate the effects of compound compatibility on the stability in gastrointestinal tract, membrane permeability and lipophilicity of panaxnotoginseng saponins (PNS).
目的：研究复方配伍对三七总皂苷（PNS）的胃肠道稳定性、膜渗透性及脂溶性的影响。
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