Like most worms, helminths synthesize chitin for their pharynx. Curious to learn how the immune system responds to such an environmentally common allergen, Locksley's team aerosolized purified chitin and sprayed it into the lungs of laboratory mice. This caused a rapid and intense immune response. To rid themselves of the chitin, the mice used the same strategy they use to respond to other allergens, in which interleukin (IL)-4 and IL-13 cells including eosinophils and basophils enter lung tissue to attack the invader. Given that the mice had not been previously exposed to chitin, Locksley wondered, “What actually sensed the chitin in the mice?”
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Like most worms, helminths synthesize chitin for their pharynx.
如同大多数蠕虫，蛔虫为自身咽部合成甲壳素。
For the same reason, filter feeders, like clams and worms, burrow underground in most regions.
同样的道理，类似蛤和虫这样的滤食动物在大部分区域都埋在地下。
Most worms in nature like to congregate in clumps, but the laboratory version of C. elegans has developed an unusual liking for being on its own.
自然界大多数蛔虫喜欢簇拥成团，但实验室里的秀丽线虫却养成了独来独往的喜好。
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