At present, the explanations for this phenomenon are: 1) ROS activated nuclear factor-KB and induction of the expression of nuclear factor-KB; 2) mitochondria-mediated cell apoptosis;
目前对这一现象有四种解释: ROS 活化核转录因子KB并诱导核转录因子-KB表达,导致细胞凋亡;
Methods Using the KB cell and resistant KB cell (KB/VCR) to vicristine, applying MTT assay, test drug sensitivity; PKC activity and effect of PKC modulators were studied in KB cell and KB/VCR.
方法:测定KB细胞及其耐药株的PKC活性及PKC调节剂对细胞药敏、药物代谢和耐药膜糖蛋白表达及其磷酸化的影响。
应用推荐