可参考右兰索拉唑延迟释放胶囊(Kapidex)的方法来设计,采用二次延迟释放技术(Dual delayed release,DDR)简单说胶囊中装两种肠溶微丸,采用不同pH的肠溶包衣,根据口服后...
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But he said more research is needed to determine which patients are likely to be most affected by the problem and whether newer proton pump inhibitors such as Aciphex and Kapidex react similarly.
但是他还说需要更多的研究来确定哪些患者最容易和最大程度受此问题影响,是否新型的质子泵抑制剂,譬如Aciphex和Kapidex也会同肝脏内比列格雷相关酶类发生类似作用。
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