"I have tried, but it is of no use; I may just as well give up at once."

“我试过了，但是没有用；我还不如马上放弃。”

youdao

"It is of no use; I cannot learn." he said in a whisper to a companion who sat near him.

“这没有用；我学不会。”他低声对坐在他旁边的同伴说。

youdao

This medicine is of no use to me.

此药对我无用。

《新英汉大辞典》

So,yes,there is a threat particularly of the use of radioactive material, although we have no specific evidence indicating any capability at this time."

VOA: standard.2009.05.01

So, if language seems exhausted because it's always preceding you, everything has always already been said, there's no new plot to be had, the world is full of stock phrases, how do you use them to embody an experience that seems fresh to you?

所以，如果因语言，在你之前就存在，而它就显得枯竭，如果一切都已经被说过，如果已没有新的情节可供创造，如果世界一直充满陈腔旧调，你如何能够用它们,呈现出一个崭新的体验？

耶鲁公开课 - 1945年后的美国小说课程节选

This is very important,which is why I am doing it: "If we want to know how fast a human being can run, then it is no use to average out the speed of a "good sample" of the population; it is far better to collect Olympic gold medal winners and see how well they can do.

这话非常重要，是我作这个研究的原因：,“如果想知道人类最快能跑多快，那从好的样本中测出平均数是“,没用的;,而应该收集田径类奥运冠军的信息,看他们能跑多快。

哈佛公开课 - 幸福课课程节选

Because the company is unprofitable, the price-to-earnings ratio is of no use here.

FORBES: Magazine Article

All passive income, which has already been taxed, is exposed to double taxation for which even the foreign tax credit is of no use.

FORBES: Americans Are Undesirable As FATCA Closes More Doors

Sure, there will be a lot that is of no use.

FORBES: The Copy-Paste Financial Plan