The fundamental knowledge regarding the molecular basis of oncogenesis provides invaluable information that is vital for the identification and development of novel biomarkers, drug targets or more effective treatments for cancer patients. In particular, dysfunction in DNA damage response and repair is a common feature in many human cancers, including colon cancers. Significantly, this feature of cancer could potentially be exploited for the development of novel diagnoses and/or treatments.
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In particular, dysfunction in DNA damage response and repair is a common feature in many human cancers, including colon cancers.
特别是，DNA损伤反应和修复的功能障碍是人类许多癌症的一个共同特征，其中包括结肠癌。
High-fat diets have been linked to obesity, and obesity is a known risk factor for a number of cancers, including postmenopausal breast, colon, kidney, and esophageal cancers.
高脂肪饮食已表明与肥胖有关，而肥胖又是一个众所周知的许多癌症的危险因素，这些癌症包括：绝经后乳腺癌、结肠癌、肾癌以及食管癌。
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