Some supplements can interfere with prescription drugs and too much can cause neuropathy and in severe cases, organ damage.

一些补品会干扰处方药的药效，过量会导致神经病变，严重的话，还会造成器官损伤。

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This may cause stomach upset, ulcers, headache, backache, high blood pressure, and in severe cases, this can lead to panic attacks or a panic disorder.

这可能会引起胃部不适、溃疡、头痛、背痛、高血压，甚至在严重的情况下，这可能导致惊恐发作或惊恐障碍。

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In severe cases, it can lead to stroke or heart attack.

有些病例会引发中风和突发性心脏病。

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Osteoarthritis is usually treated with pain relievers and anti-inflammatory drugs, but in severe cases, the damaged joint can be replaced with an artificial one.

VOA: standard.2010.08.11

In very severe cases, it can even defile some common objects, and in those cases, the source of impurity might have to be isolated or excluded if necessary.

在一些非常严峻的情况中，它会玷污一些普通的事物，在这种时候，不洁之源,也许只能被孤立，严重的话需要驱逐。

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And as I mentioned before, death would occur in 20-30 percent of the cases that got the most severe form of smallpox.

就像我刚说的,百分之二十到三十的,天花重症病人会死亡

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In severe cases the pain lasts for years and can make ordinary sensations unbearable.

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In severe cases, symptoms can set in within four hours, and death follows swiftly.

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An antihistamine such as Benadryl will be given and, in severe cases, a shot of epinephrine.

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