2 人源化抗体(humanized antibody) 又称重构型抗体、 改型抗体(reshaped antibody) 或 CDR 移植抗体(CDR grafting antibody) : 通过置换三个发夹状环的鼠抗体超变区...
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习题内容 抗体分子，从而增强抗体免疫治疗的效应。 （二）改型抗体（reshaped antibody，RAb）制备人源化抗体（humanized antibody，HAb）的主要目的是减少抗体的异源性，有利于其临床应用。嵌合抗体的免疫原性要比鼠单抗明显降低，但可变区中仍保
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humanized antibody library 人源化噬菌体抗体库
humanized monoclonal antibody 单株抗体 ; 人源单克隆抗体
humanized d antibody 人源化抗体
humanized single chain antibody 人源化单链抗体
humanized genetic engineering antibody 人源化基因工程抗体
humanized anti-HER2 monoclonal antibody 抗HER2人源化单克隆抗体
anti-CD20 functionally humanized monoclonal antibody 抗CD20单克隆抗体
humanized recombined cd monoclonal antibody 人源化抗cd25单克隆抗体
The course of humanize mouse monocloal antibodies has four steps: human and mouse chimeric antibody ,the humanized antibody ,the antibody from phage antibody library,the human antibody expressing from transgenic animnals.
鼠源抗体的人源化改造过程历经：人鼠嵌和抗体、人源化抗体、噬菌体抗体库、转基因动物表达人抗体四个阶段。
参考来源 - 人免疫球蛋白Cγ·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
Because this method was to simulate the process of antibody maturation in vivo, the obtained antibodies was not only fully humanized but also with relatively high affinity.
该方法体外模拟了抗体亲和力成熟的过程，使得到的抗体不但可以完全的人源化，而且可以具有较高的亲和力。
We must prove that there is really brain glioma antibody in the blood of patients, then we can establish the base for constructing humanized phage antibody library.
为了构建人源性抗脑胶质瘤抗体库，我们必须先从患者的血液内检测到抗脑胶质瘤抗体，才能为建立人源性噬菌体抗体库奠定基础。
But it is difficult to make humanized monoclonal antibody with hybridoma technique. Antibody library technique coming forth in the early 90s provides the new method to get the antibody.
采用杂交瘤技术制备人源性单克隆抗体存在许多困难，90年代初期出现了抗体库技术，为抗体的制备提供了新的途径。
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