The regulation of HIF 1 activity is the focus of hypoxia responsive genes expression.
HIF 1自身活性调节是低氧应答基因表达调控的中心环节。
The influencing of some oncogene and anti-oncogene to the expression and activity of HIF-1 determines neoplastic prognosis ultimately.
而某些癌基因和抑癌基因对HIF-1表达及活性的影响最终决定着肿瘤的预后。
Hypoxia activates hypoxia-inducible factor 1 (HIF-1), thus it controls a series of expression of genes correlated with hypoxia.
低氧可激活低氧诱导因子(HIF - 1)，从而调控一系列与缺氧相关基因的表达。
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