They've got to do something about these children because clearly they've gone off the rails.

他们必须对这些孩子采取点行动，因为很明显他们的行为已经出轨了。

《柯林斯英汉双解大词典》

He is a very reliable person he has never gone off the rails.

他这人十分可靠，从来不越轨逾矩。

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He used to be a very reliable and trustworthy person, but he has gone off the rails recently.

他以前是个非常诚实可靠的人，可是近来走上了邪路。

youdao

Could she really have allowed her young daughter to have gone off the rails in such a way?

BBC: 'Stormy' dilemma for Republicans

My take on Bartlett: A once-fine thinker who has gone off the rails.

FORBES: Did Bush Blow Free Trade?

And O'Sullivan admitted that he had gone off the rails after winning the European Open and Irish Masters titles in March.

BBC: O'Sullivan returns to form