...变,可得到基因剔除小鼠(gene knockout mice);将小鼠的基因组中特定内源基因进行定向重组,可得到基因替换小鼠(gene knockin mice).为医学研究提供了丰富的动物模型.
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页面: 中文名称: 基因敲入 英文名称: gene knockin 别 名: 基因引入,gene knock-in 词 性: 名词 中文解释: 在基因组特定位置引入外...) 第1行: 第1行: -
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Gene knockin
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abstract:
In molecular cloning and biology, a Knock-in (or Gene knock-in) refers to a genetic engineering method that involves the insertion of a protein coding cDNA sequence at a particular locus in an organism's chromosome. Typically, this is done in mice since the technology for this process is more refined, and because mouse embryonic stem cells are easily manipulated.
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