full of ups and downs 三十年河东三十年河西 life is full of ups and downs 生活充满起伏 several ups and downs 几起几落 .
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The course of life never runs smoothly for it is full of ups and downs and twists and turns.
人生之路从不一帆风顺，因为它充满了起伏与曲折。
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Life is full of ups and downs.
生活是曲折的。
《新英汉大辞典》
Why is my life always full of ups and downs?
为什么我的生活充满了曲折。
It was a week full of high drama, foolishness, tragedy and many ups and downs (for a variety of reasons).
FORBES: 'Two Faces Have I: One To Laugh And One To Cry' (And Other Quotes Of The Week)
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