FLT3L is produced by t cells and stromal fibroblasts (1, 2).
FLT3L是通过t细胞和基质纤维原细胞产生(1,2)。
Binding of FLT3L to its cognate tyrosine kinase receptor, FLT3, activates STAT3 and STAT5 (1, 3).
FLT3L结合到与它同源的酪氨酸激酶的受体FLT3结合激活STAT3和STAT 5 (1,3)。
FLT3L in combination with other factors stimulates differentiation and proliferation of hematopoietic multipotent progenitors and promotes proliferation of NK cells and dendritic cell subsets.
FLT3L与其他的因子结合刺激多能造血细胞的起源并促进NK细胞和树状系列细胞的增殖。
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